At the Humphrey Lab, part of Mount Sinai in New York City, we harness advanced computational tools to explore the genetic and molecular underpinnings of neurodegenerative diseases — progressive and often fatal conditions affecting the brain.

Our primary focus is on Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD), two closely related disorders characterized by shared genetic and pathological features. Join us as we delve into the intricate connections between these diseases to pave the way for innovative research and potential treatments.